An international expert opinion on the management of azole-resistant aspergillosis was recently published [Drug Resist Updat 2015;21-22:30-40]. In the absence of published guidelines, experts discussed the optimal treatment options in patients with documented azole-resistant invasive aspergillosis and the primary treatment choice in regions with environmental azole resistance. The experts recommended routine in vitro susceptibility testing of Aspergillus fumigatus isolates recovered from patients in whom antifungal therapy is considered.